Two-Dimensional-Based Hybrid Shape Optimisation of a 5-Element Formula 1 Race Car Front Wing under FIA Regulations

Front wings are a key element in the aerodynamic performance of Formula 1 race cars. Thus, their optimisation makes an important contribution to the performance of cars in races. However, their design is constrained by regulation, which makes it more difficult to find good designs. The present work develops a hybrid shape optimisation approach to obtain an optimal five-element airfoil front wing under the FIA regulations and 17 design parameters. A first baseline design is obtained by parametric optimisation, on which the adjoint method is applied for shape optimisation via Mesh Morphing with Radial Basis Functions. The optimal front wing candidate obtained outperforms the parametric baseline up to a 25% at certain local positions. This shows that the proposed and tested hybrid approach can be a very efficient alternative. Although a direct 3D optimisation approach could be developed, the computational costs would be dramatically increased (possibly unaffordable for such a complex five-element front wing realistic shape with 17 design parameters and regulatory constraints). Thus, the present approach is of strong interest if the computational budget is low and/or a fast new front wing design is desired, which is a frequent scenario in Formula 1 race car design.The authors want to acknowledge the financial support from the Ramón y Cajal 2021 Excellence Research Grant action from the Spanish Ministry of Science and Innovation (FSE/AGENCIA ESTATAL DE INVESTIGACIÓN), the UMA18-FEDERJA-184 grant, and the Andalusian Research, Development and Innovation Plan (PAIDI—Junta de Andalucia) fundings. Partial funding for open access charge: Universidad de Málag

Treatment with tocilizumab or corticosteroids for COVID-19 patients with hyperinflammatory state: a multicentre cohort study (SAM-COVID-19)

Objectives: The objective of this study was to estimate the association between tocilizumab or corticosteroids and the risk of intubation or death in patients with coronavirus disease 19 (COVID-19) with a hyperinflammatory state according to clinical and laboratory parameters. Methods: A cohort study was performed in 60 Spanish hospitals including 778 patients with COVID-19 and clinical and laboratory data indicative of a hyperinflammatory state. Treatment was mainly with tocilizumab, an intermediate-high dose of corticosteroids (IHDC), a pulse dose of corticosteroids (PDC), combination therapy, or no treatment. Primary outcome was intubation or death; follow-up was 21 days. Propensity score-adjusted estimations using Cox regression (logistic regression if needed) were calculated. Propensity scores were used as confounders, matching variables and for the inverse probability of treatment weights (IPTWs). Results: In all, 88, 117, 78 and 151 patients treated with tocilizumab, IHDC, PDC, and combination therapy, respectively, were compared with 344 untreated patients. The primary endpoint occurred in 10 (11.4%), 27 (23.1%), 12 (15.4%), 40 (25.6%) and 69 (21.1%), respectively. The IPTW-based hazard ratios (odds ratio for combination therapy) for the primary endpoint were 0.32 (95%CI 0.22-0.47; p < 0.001) for tocilizumab, 0.82 (0.71-1.30; p 0.82) for IHDC, 0.61 (0.43-0.86; p 0.006) for PDC, and 1.17 (0.86-1.58; p 0.30) for combination therapy. Other applications of the propensity score provided similar results, but were not significant for PDC. Tocilizumab was also associated with lower hazard of death alone in IPTW analysis (0.07; 0.02-0.17; p < 0.001). Conclusions: Tocilizumab might be useful in COVID-19 patients with a hyperinflammatory state and should be prioritized for randomized trials in this situatio

Two-Dimensional-Based Hybrid Shape Optimisation of a 5-Element Formula 1 Race Car Front Wing under FIA Regulations

Front wings are a key element in the aerodynamic performance of Formula 1 race cars. Thus, their optimisation makes an important contribution to the performance of cars in races. However, their design is constrained by regulation, which makes it more difficult to find good designs. The present work develops a hybrid shape optimisation approach to obtain an optimal five-element airfoil front wing under the FIA regulations and 17 design parameters. A first baseline design is obtained by parametric optimisation, on which the adjoint method is applied for shape optimisation via Mesh Morphing with Radial Basis Functions. The optimal front wing candidate obtained outperforms the parametric baseline up to a 25% at certain local positions. This shows that the proposed and tested hybrid approach can be a very efficient alternative. Although a direct 3D optimisation approach could be developed, the computational costs would be dramatically increased (possibly unaffordable for such a complex five-element front wing realistic shape with 17 design parameters and regulatory constraints). Thus, the present approach is of strong interest if the computational budget is low and/or a fast new front wing design is desired, which is a frequent scenario in Formula 1 race car design

Two-Dimensional-Based Hybrid Shape Optimisation of a 5-Element Formula 1 Race Car Front Wing under FIA Regulations

Front wings are a key element in the aerodynamic performance of Formula 1 race cars. Thus, their optimisation makes an important contribution to the performance of cars in races. However, their design is constrained by regulation, which makes it more difficult to find good designs. The present work develops a hybrid shape optimisation approach to obtain an optimal five-element airfoil front wing under the FIA regulations and 17 design parameters. A first baseline design is obtained by parametric optimisation, on which the adjoint method is applied for shape optimisation via Mesh Morphing with Radial Basis Functions. The optimal front wing candidate obtained outperforms the parametric baseline up to a 25% at certain local positions. This shows that the proposed and tested hybrid approach can be a very efficient alternative. Although a direct 3D optimisation approach could be developed, the computational costs would be dramatically increased (possibly unaffordable for such a complex five-element front wing realistic shape with 17 design parameters and regulatory constraints). Thus, the present approach is of strong interest if the computational budget is low and/or a fast new front wing design is desired, which is a frequent scenario in Formula 1 race car design

Experiencias de Aprendizaje-Servicio en la UPM: 2021 y 2022

La Oficina de Aprendizaje-Servicio (ApS) de la UPM, constituida en sesión del Consejo de Gobierno de diciembre de 2019 tiene, como misión fundamental, promover en el ámbito de las enseñanzas de esta universidad la metodología ApS. Con esta finalidad se vienen realizando convocatorias de proyectos de impacto social alineados con los ODS como un mecanismo más para la contribución a la Agenda 2030, y se colabora intensamente con las diversas oficinas constituidas con el mismo objetivo en otras universidades. Nuestra oficina pretende impulsar progresivamente la colaboración con entidades ajenas a la UPM, y atender demandas y necesidades sociales en las que nuestros estudiantes y profesores brinden sus conocimientos para la construcción de una mejor y más justa sociedad. Con este propósito, se han puesto en marcha numerosas iniciativas y colaboraciones con Ayuntamientos, Asociaciones, ONG, Fundaciones y centros de enseñanza, con el fin común de plantear mejoras y trabajar con entornos desfavorecidos, y colectivos vulnerables de nuestro entorno. Cabe destacar la muy positiva acogida que, progresivamente se está logrando, en lo relativo a la diseminación de estas iniciativas en el ámbito de la UPM, viéndose incrementada la participación e interés de nuestros docentes y estudiantes en los llamamientos que se realizan desde la oficina. Desde la constitución de la oficina, son ya más de 100 actividades desarrolladas con la participación de más de 500 profesores. Uno de los compromisos de la Oficina ApS de la UPM es dar visibilidad por su carácter meritorio a las experiencias realizadas por el profesorado y los estudiantes de nuestra universidad y, es por ello, que nos complace la presentación de esta primera edición del ebook, en el que se recogen algunas de las experiencias realizadas en nuestra universidad y que confiamos ampliar periódicamente con futuras ediciones. Nuestro más sincero agradecimiento a todos los profesores que habéis hecho posible esta primera publicación con vuestras contribuciones